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10.3389/fendo.2023.1244432 131 XuG.StoffersD

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Additionally, the upregulation of inflammation-related genes, such as IL-6 and TNF-, is associated with the pathological state of depression, suggesting that immune responses play a critical role in its pathogenesis [365, 366]

We gratefully acknowledge the assistance of Dara Alexander and Christine Bright, from The ALS Association's Florida Chapter, in enrolling ALS patients in our study

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